Past Projects

Past COSSAC projects can be found in this section as well as projects that were completed at the Advanced Computation Laboratory at Cancer Research UK, which fed into or influenced work being undertaken by COSSAC.

Argumentation Service Platform with Integrated Components.
The development of knowledge-based services based on semantically rich logic formalisms called Argumentation Systems. Supported by EU Sixth Framework IST Programme, 2004-2007
Home monitoring through intelligent dialog system
Development and deployment of telemedicine services based on an IDS (Intelligent Dialog System). Supported by the EU 5th Framework IST Programme (Information Society Technologies) (2001-4).
Leukaemia Information System and Advice
Development and deployment of decision-support tools to improve survival in childhood Acute Lymphoblastic Leukaemia. Supported by Cancer Research UK, 2001-4.
Early Referrals Applications.
Early Referrals Application for patients with suspected cancer. Developmment and evaluation of 12 web-enabled early referral cancer guidelines. The ERA application was developed by the ACL. ERA is now being piloted by the UK NHS Information Authority.
Computer Aided Decision Making and Image Understanding in Medicine.
CADMIUM focuses on two areas of medical computing: digital image processing and decision support systems. A prototype radiology workstation has been developed, along with demonstrator applications in mammography and the management of neuroblastoma. Co-ordinated by CHIME , the Centre for Health Informatics & Multiprofessional Education, University College, London, and part-funded by the EPSRC. (CADMIUM I: 1993-96; CADMIUM II: 1998-2001.)
Risk Assessment and Genetic counselling.
The RAGs project developed a system to assess genetic risk in breast and ovarian cancer, and to support professional counsellors helping people make personal healthcare decisions in these areas. RAGs applied decision theories and technologies developed in the StAR and PROMPT projects, and cognitive models and theories of risk perception from the COGENT project. A collaboration between the ACL and Imperial Cancer Research Fund (now Cancer Research UK) units in London, Oxford and Edinburgh, and supported by the UK Economic and Social Research Council programme in cognitive engineering and the Imperial Cancer Research Fund (1996-2000).
PROtocols for Medical Procedures and Therapies.
PROMPT developed and evaluated components for a clinical care station (principally the PROforma clinical guideline authoring and enactment environemnt and a French electronic patient record system. PROMPT, a successor project to Dilemma, was co-ordinated by the ACL and funded under the EC Fourth Framework Telematics Applications Programme (1996-9). Main collaborators were the Institut BergoniƩ (Bordeaux) and Erasmus University (Rotterdam).
New Techniques for Risk Assessment.
StAR (Standardised Argument Report) applied theoretical work undertaken by the ACL on "argumentation" (as a technique for knowledge based reasoning under uncertainty) to the problems of risk assessment and communication. The practical focus of the work was in assessing the risk of chemical compounds causing cancer, but the technology developed was designed to be of general applicability. Supported by the Engineering and Physical Sciences Research Council and Department of Trade and Industry (1993-6).
Rigorously Engineered Decisions.
RED investigated techniques for developing high integrity and provably safe computer software. To achieve this, established formal methods from software engineering were combined with novel AI techniques for dynamic reasoning about the safety of clinical actions. RED complemented Dilemma and PROMPT by providing the theoretical underpinning to the clinical applications developed in these projects. Part-funded by the Engineering and Physical Sciences Research Council and Department of Industry, and co-ordinated by Lloyds' Register (1992-95).
Decision Support in Primary Care, Oncology and Shared Care.
Dilemma followed up work carried out under the EU LEMMA project on the development and application of a generic technology for supporting healthcare professionals in making clinical decisions and managing patients in general practice, hospital care and shared care. The main application focus was oncology, but substantial applications were also built in cardiology and general practice. Dilemma was a collaboration of eight European partners, part-funded under the EC 3rd Framework Health Telematics programme (1992-95). It was co-ordinated by the ACL.